Really interesting map based on 2010 census that details areas of the United States where there are no people living.
Source: Maps By Nik
A Block is the smallest area unit used by the U.S. Census Bureau for tabulating statistics. As of the 2010 census, the United States consists of 11,078,300 Census Blocks. Of them, 4,871,270 blocks totaling 4.61 million square kilometers were reported to have no population living inside them. Despite having a population of more than 310 million people, 47 percent of the USA remains unoccupied.